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Early development of rubrospinal and cerebellorubral projections in Xenopus laevis
H J ten Donkelaar1, R de Boer-van Huizen, J A van der Linden
1Department of Anatomy and Embryology, University of Nijmegen, The Netherlands.
Brain Research. Developmental Brain Research
|February 22, 1991
Abstract:
In Xenopus laevis HRP was applied at the spinomedullary border at various stages of development. In these experiments labeled rubrospinal neurons were observed from stage 48 on. HRP applications to the mesencephalic tegmentum showed, from stage 49 on, retrogradely labeled neurons in the cerebellar nucleus, particularly contralaterally. These data suggest that anuran cerebellorubral projections arise early, well before the rubrospinal innervation of the spinal cord is complete.