Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Conventional electromyography in myotonic dystrophy.

G Caruso, E Ferrannini

Rivista Di Patologia Nervosa E Mentale

|September 1, 1976

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Predictors of type 2 diabetes relapse after Roux-en-Y Gastric Bypass: A ten-year follow-up study.

Diabetes & metabolism·2021

Same author

Mannose is an insulin-regulated metabolite reflecting whole-body insulin sensitivity in man.

Metabolism: clinical and experimental·2019

Same author

Impaired beta cell sensitivity to incretins in type 2 diabetes is insufficiently compensated by higher incretin response.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2017

Same author

Obesity and carotid artery remodeling.

Nutrition & diabetes·2015

Same author

The amino acid response to a mixed meal in patients with type 2 diabetes: effect of sitagliptin treatment.

Diabetes, obesity & metabolism·2014

Same author

Type 1 diabetes and (C-X-C motif) ligand (CXCL) 10 chemokine.

La Clinica terapeutica·2014

Same journal

[Action mechanism of antidepressive drugs. Review of current knowledge].

Rivista di patologia nervosa e mentale·1984

Same journal

[Opsoclonus-ataxia syndrome. Description of a case].

Rivista di patologia nervosa e mentale·1984

Same journal

[Neurological complications in Behçet's disease].

Rivista di patologia nervosa e mentale·1984

Same journal

[Multiple intracranial aneurysms associated with arteriovenous malformation. Clinical case].

Rivista di patologia nervosa e mentale·1984

Same journal

[Drop attack as the only symptom of type 1 Chiari malformation. Illustration by a case].

Rivista di patologia nervosa e mentale·1984

Same journal

[Recited depression].

Rivista di patologia nervosa e mentale·1984

See all related articles

Myotonic dystrophy patients exhibit abnormal muscle electrical activity, including myotonic discharges. Nerve conduction studies in these patients remained normal, suggesting nerve changes are secondary to the primary genetic defect.

Area of Science:

Neurology
Clinical Electrophysiology
Genetics

Background:

Myotonic dystrophy is a multisystem genetic disorder.
Understanding the underlying pathophysiology is crucial for diagnosis and management.

Purpose of the Study:

To investigate the electromyographic (EMG) findings and nerve conduction velocities in patients with myotonic dystrophy.
To explore the relationship between muscle and nerve abnormalities in the disease.

Main Methods:

Electromyography (EMG) was performed on brachial biceps, extensor digitorum communis, and tibialis anterior muscles in 31 subjects.
Motor and sensory nerve conduction velocities were measured in the median nerve of 14 patients.

Main Results:

Related Experiment Videos

EMG revealed abnormal interference patterns, prolonged 'after discharges', and increased polyphasic potentials during muscle effort.

Spontaneous activity and positive sharp waves were observed at rest in approximately 50% of patients.

Myotonic/pseudomyotonic discharges occurred in all subjects, while nerve conduction velocities were consistently normal.

Conclusions:

EMG findings suggest significant myopathy in myotonic dystrophy.
Normal nerve conduction velocities indicate that nerve changes are likely secondary to the primary genetic defect and not a primary neuronal cause of muscle wasting.