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Related Experiment Video

Updated: Jun 14, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Erythrodermic atopic dermatitis with late onset--case presentation.

Cristina Lancrajan¹, Roxana Bumbacea, Calin Giurcaneanu

¹Camrol Davila University of Medicine and Pharmacy-Bucharest, Romania.

Journal of Medicine and Life

|March 23, 2010

Summary

This case study highlights a rare late-onset atopic dermatitis (AD) presentation in a young adult. Prompt recognition and combined therapy successfully managed severe symptoms, emphasizing lifestyle adjustments for recurrence prevention.

Related Experiment Videos

Last Updated: Jun 14, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Area of Science:

Dermatology
Immunology

Background:

Atopic dermatitis (AD) is a chronic inflammatory skin condition often linked to allergic comorbidities and childhood onset.
Elevated serum IgE is common in AD patients, though not universally present.

Observation:

A 21-year-old female presented with severe, generalized eczematous lesions, lichenification, pruritus, and scalp plaques.
Notably, she lacked personal or family history of atopy, and symptoms had a recent severe exacerbation over 3 years.
Laboratory results revealed significant eosinophilia and markedly elevated total IgE serum levels.

Findings:

The patient's presentation mimicked erythroderma, underscoring the importance of considering late-onset AD.
Treatment involved a multimodal approach including systemic corticosteroids, antihistamines, antibiotics, UVB phototherapy, topical steroids, and hydration.
Successful remission was achieved with this combined therapeutic strategy.

Implications:

Recognizing AD as a potential cause of erythroderma, particularly in late-onset cases, is crucial for timely and effective management.
Patient education on lifestyle modifications and early symptom recognition is vital for preventing disease recurrence.
This case expands the understanding of AD's diverse clinical presentations and management challenges.