Value of ultrasound in evaluation of infants with first urinary tract infection

Iulian Preda1, Ulf Jodal, Rune Sixt

  • 1Department of Pediatrics, Queen Silvia Children's Hospital, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

The Journal of Urology
|March 23, 2010
PubMed

Insights

Ultrasound effectively identifies many urinary tract abnormalities in infants but misses some cases of grade III reflux. This noninvasive imaging is valuable for diagnosing infant urinary tract infections, particularly when prenatal screening is limited.

Area of Science:

  • Pediatric Nephrology
  • Diagnostic Imaging
  • Infant Urology

Background:

  • Urinary tract infections (UTIs) in infants can lead to significant renal damage.
  • Early diagnosis and management are crucial to prevent long-term complications.
  • Identifying structural abnormalities is key in managing infant UTIs.

Purpose of the Study:

  • To assess the diagnostic utility of ultrasound in infants with a first UTI.
  • To identify important structural urinary tract abnormalities.
  • To evaluate ultrasound's role in conjunction with other imaging modalities.

Main Methods:

  • A prospective, population-based study of 290 infants (161 male, 129 female) with a first UTI.
  • Initial investigations included ultrasound and dimercapto-succinic acid scintigraphy.
  • Voiding cystourethrography was performed within two months for further evaluation.

Main Results:

  • Ultrasound detected dilatation in 15% and increased kidney length in 28% of infants.
  • Sensitivity for detecting scintigraphic abnormalities was 48%; renal length correlated with inflammatory markers.
  • Ultrasound identified 30 of 40 significant structural abnormalities, missing 10 cases of dilating reflux (mostly grade III).

Conclusions:

  • Ultrasound is a valuable, noninvasive tool for evaluating infants with UTIs, detecting most structural abnormalities except high-grade reflux.
  • Its use is particularly recommended in settings with limited prenatal ultrasound screening.
  • Further research is needed to explore the clinical significance of renal length correlation with inflammatory parameters in acute UTI.
Abstract

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