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Updated: Jun 14, 2026

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Extensions of the sphenoid sinus: a new classification
Jian Wang1, Sharatchandra Bidari, Kohei Inoue
1Department of Neurosurgery University of Florida Gainesville, Florida, USA.
Neurosurgery
|March 23, 2010
Summary
Pneumatized extensions of the sphenoid sinus create surgical "windows." Understanding these variations aids minimally invasive approaches to cranial base lesions.
Area of Science:
- Neurosurgery
- Anatomy
- Radiology
Background:
- The transsphenoidal approach is increasingly used for lesions beyond the sellar region.
- Extended approaches now target areas like the cavernous sinus, Meckel's cave, and clivus.
Purpose of the Study:
- To investigate pneumatized extensions of the sphenoid sinus.
- To identify anatomical variations that facilitate extended transsphenoidal approaches.
Main Methods:
- Examination of 18 cadaver heads.
- Correlation with 100 computed tomography (CT) scans of the sphenoid sinus.
- Classification of sphenoid sinus sellar types based on pneumatization.
Main Results:
- Six basic types of sphenoid sinus pneumatization were identified: body, lateral, clival, lesser wing, anterior, and combined.
- Pneumatized recesses and prominences act as natural "windows" to adjacent cranial base areas.
- These anatomical features offer potential for minimally invasive surgical access.
Conclusions:
- Variations in sphenoid sinus pneumatization are crucial for surgical planning.
- These extensions can facilitate access to lesions bordering the sphenoid sinus.
- Understanding these anatomical variations aids in selecting optimal surgical approaches.
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