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Direct determination of molecular haplotypes by chromosome microdissection
1Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia, USA.
Nature Methods
|March 23, 2010
Abstract
None:
Direct observation of haplotypes is still technically challenging. Here we report a method for the determination of haplotypes through chromosome microdissection. We determined human long-range chromosomal haplotypes with more than 98.85% accuracy at 24,245 genome-wide heterozygous single-nucleotide polymorphism (SNP) loci.
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