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Updated: Jun 14, 2026

A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury
Published on: March 31, 2023
Aortic valve repair for congenital and balloon-induced aortic regurgitation
1Cardiac Surgery, Children's National Medical Center, Washington, DC, USA. rjonas@cnmc.org
Abstract:
Current techniques for aortic valve replacement in the child carry multiple disadvantages. Longer-term follow-up of the Ross procedure has documented disappointing late results for an increasing proportion of patients. Many challenges continue to face the development of a tissue-engineered valve with growth potential. In this setting, aortic valve repair is a useful temporizing procedure that allows a child to have an excellent quality of life, free from the need for anticoagulation and the risk of thromboembolism. Repair techniques are primarily based on the use of autologous pericardium to extend leaflets and support prolapsing leaflets. These methods appear to be particularly applicable in the setting of balloon-induced aortic valve regurgitation. An increasing number of centers are reporting satisfactory midterm results with aortic valve repair.
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