Related Experiment Video
Updated: Jun 14, 2026

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
Published on: July 11, 2025
Plasmodium vivax susceptibility to ferroquine
M L Leimanis1, A Jaidee, K Sriprawat
1Shoklo Malaria Research Unit, Mae Sot, Tak, Thailand. mara@tropmedres.ac
Abstract:
The novel organometallic chloroquine analog ferroquine (SSR 97193) is effective against chloroquine-resistant Plasmodium falciparum. The ex vivo efficacy of ferroquine against Plasmodium vivax isolates was tested. Ferroquine has a potent ex vivo effect on P. vivax schizont maturation (median 50% inhibitory concentration, 15 nM; n = 42). No significant cross-sensitivity between ferroquine and other antimalarials was detected. This drug may be a suitable replacement for chloroquine in the treatment of drug-resistant P. vivax malaria.
Related Concept Videos
Malaria
Symbiosis
Antiprotozoal Agents
Diversity of Protists II
Anthelminthic Agents
Rocky Mountain Spotted Fever

