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Iris metastasis from a bronchial carcinoid tumor.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|January 1, 1978
Summary
A rare case of iris metastasis from bronchial carcinoid tumor was diagnosed in a 54-year-old man. Surgical excision was successful, with the patient remaining well years later.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- A 54-year-old male presented with a vascularized iris mass.
- He had a history of a stable pulmonary nodule observed for five years.
Observation:
- The iris mass exhibited early vascular filling and diffuse staining on fluorescein angiography.
- A radioactive phosphorus (32P) uptake test was positive.
- Initial clinical diagnosis considered iris melanoma or metastasis.
Findings:
- Microscopic examination revealed tumor cells with neurosecretory granules, lacking melanin.
- Special stains for melanin and argentaffin/argyrophil substances were negative.
- Electron microscopy confirmed the presence of neurosecretory granules.
Implications:
- The findings confirmed iris metastasis from a probable bronchial carcinoid tumor.
- This case highlights the importance of considering metastatic disease in iris lesions.
- Successful surgical management (iridocyclectomy) led to a favorable long-term outcome.