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Adenoid cystic carcinoma developing in the nasal orbit
J A Shields1, C L Shields, R C Eagle
1Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.
American Journal of Ophthalmology
|March 1, 1997
Summary
A rare case of adenoid cystic carcinoma in the medial orbit is presented. This tumor, typically found in the lacrimal gland, can also occur in the nasal orbit and should be considered in differential diagnoses.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Adenoid cystic carcinoma (ACC) is a malignant tumor that can occur in various organs, including the orbit.
- Orbital ACC most commonly arises from the lacrimal gland, typically in the superotemporal region.
- Differential diagnosis of orbital masses is crucial for appropriate management.
Observation:
- A 26-year-old male presented with a painless soft tissue mass in the medial (nasal) aspect of the left orbit.
- Computed tomography (CT) revealed a 1.5 cm antronasal mass without bone erosion.
- Incisional biopsy confirmed the diagnosis of adenoid cystic carcinoma.
Findings:
- Histopathologic examination confirmed adenoid cystic carcinoma.
- The tumor's location in the medial orbit is atypical, as ACC usually originates from the lacrimal gland in the superotemporal orbit.
- The presence of ectopic lacrimal gland tissue is a possible explanation for this unusual location.
Implications:
- This case highlights that adenoid cystic carcinoma can occur in the nasal orbit, not exclusively from the main lacrimal gland.
- Clinicians should consider ACC in the differential diagnosis of tumors presenting in the nasal orbit.
- Accurate diagnosis and understanding of tumor origin are vital for effective treatment planning and patient outcomes.
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