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Are the hepatic arteries "end arteries"?
1Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories.
Investigative Radiology
|April 1, 1991
Summary
This study reveals extensive intrahepatic arterial networks in human livers. These interconnected vessels explain the rarity of liver infarcts and the spread of liver cancer.
Area of Science:
- Vascular Anatomy
- Radiology
- Hepatobiliary System
Background:
- Intrahepatic arterial anastomoses are crucial for liver function and pathology.
- Understanding these pathways aids in diagnosing and explaining various liver conditions.
Purpose of the Study:
- To investigate and delineate the interconnecting arterial pathways within the human liver.
- To correlate these findings with clinical observations such as hepatic infarcts and tumor spread.
Main Methods:
- Autopsy livers (n=25) were analyzed using fluoroscopy-guided injection of barium suspension.
- High-resolution radiography of liver sections was performed after arterial injection.
- Radiographs were meticulously reviewed to identify and map arterial pathways.
Main Results:
- Seven distinct intrahepatic arterial networks were identified, including arcades, connecting vessels, and parenchymal networks.
- Demonstrated complete liver filling even with branch artery occlusion, highlighting collateral circulation.
- Identified connections with the gallbladder arterial system.
Conclusions:
- The identified arterial networks explain the low incidence of hepatic infarcts.
- These pathways provide the anatomical basis for intrahepatic metastasis of malignant lesions.
- The findings may elucidate arteriographic patterns like "duplication," "triplication," and the "thread and streak" sign in hepatocellular carcinoma with portal vein invasion.