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Related Experiment Video

Updated: Jun 14, 2026

A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
04:55

A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse

Published on: November 17, 2016

Limbal Stem Cell Transplantation for Limbal Dermoid.

Samin Hong, Eun-Ji Kim, Gong Je Seong

    Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
    |March 27, 2010
    PubMed
    Summary

    Limbal dermoids, benign tumors on the cornea, can impair vision. Autologous limbal stem cell transplantation offers a promising treatment for these challenging cases, yielding positive outcomes.

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    Area of Science:

    • Ophthalmology
    • Regenerative Medicine
    • Corneal Surgery

    Background:

    • Limbal dermoids are congenital benign tumors located at the limbus.
    • They can cause significant cosmetic concerns and visual impairment.
    • Surgical management for deep dermoids may involve complex procedures like keratoscleroplasty.

    Purpose of the Study:

    • To evaluate the efficacy of autologous limbal stem cell transplantation in managing limbal dermoids.
    • To present surgical outcomes in two cases of limbal dermoid excision and reconstruction.

    Main Methods:

    • Autologous limbal stem cell transplantation.
    • Surgical excision of limbal dermoids.
    • Corneal and scleral reconstruction techniques.

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    Last Updated: Jun 14, 2026

    A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
    04:55

    A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse

    Published on: November 17, 2016

    Isolation and Identification of Limbal Niche Cells
    10:11

    Isolation and Identification of Limbal Niche Cells

    Published on: October 27, 2023

    Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells
    11:13

    Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

    Published on: April 7, 2016

    Main Results:

    • Successful removal of limbal dermoids in both cases.
    • Good visual outcomes and cosmetic improvement post-transplantation.
    • No significant intraoperative or postoperative complications reported.

    Conclusions:

    • Autologous limbal stem cell transplantation is a viable and effective treatment for limbal dermoids.
    • This technique offers a good alternative for reconstruction after dermoid excision.
    • Further studies are warranted to confirm long-term efficacy.