Related Experiment Video
Updated: Jun 14, 2026
15:49
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Colonic polyposis due to Schistosoma intercalatum
Azucena Rodríguez-Guardado1, Rosa Miquel, Francisco Pérez
1Unidad de Enfermedades Infecciosas, Hospital Universitario Central de Asturias, C/Celestino Villamil s/n 33006, Oviedo, Spain. azucenarodriguez@telecable.es
Summary
Schistosomiasis polyps are common with Schistosoma mansoni and S. japonicum but not S. intercalatum. This case highlights colonic polyposis in a patient with S. intercalatum infection.
Area of Science:
- Tropical medicine
- Parasitology
- Gastroenterology
Background:
- Schistosomiasis is a parasitic disease caused by flatworms of the genus Schistosoma.
- Colonic schistosomiasis, particularly by Schistosoma intercalatum, is typically associated with mild gastrointestinal symptoms.
- Previous reports link Schistosoma mansoni and S. japonicum infections to polyp formation in the colon.
Observation:
- A case study of a 17-year-old male from Equatorial Guinea is presented.
- The patient presented with colonic polyposis, a condition characterized by the development of multiple polyps in the colon.
- This observation is unusual as colonic schistosomiasis due to S. intercalatum has not been previously associated with polyp formation.
Findings:
- The patient was diagnosed with Schistosoma intercalatum infection.
- The colonic polyposis was found to be associated with this specific parasitic infection.
- This represents a novel pathological finding for S. intercalatum-induced schistosomiasis.
Implications:
- This case expands the known clinical spectrum of Schistosoma intercalatum infection.
- It suggests that S. intercalatum can induce significant colonic pathology, including polyposis.
- Further research is warranted to understand the mechanisms behind S. intercalatum-induced polyposis and its clinical significance.
Related Concept Videos
01:27Diverticular Disease of the Colon
Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
01:17Chronic Bowel Disorders: Introduction
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
01:28Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
01:26Inflammatory Bowel Disease I: Introduction
Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
01:20Inflammatory Bowel Disease II: Ulcerative Colitis
Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
01:21Inflammatory Bowel Disease V: Surgical Management
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD: