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Takotsubo cardiomyopathy following dipyridamole pharmacologic stress

Angela S Koh1, Henry Kok, Terrance Chua

  • 1Department of Cardiology, National Heart Centre, Mistri Wing, Third Hospital Avenue, Singapore 168752, Singapore. just9me@yahoo.com

Annals of Nuclear Medicine
|March 27, 2010
PubMed

Insights

This case report details an elderly woman with rapid atrial fibrillation who developed temporary Takotsubo cardiomyopathy after dipyridamole stress testing. This finding, observed via myocardial perfusion imaging, resolved within a month.

Area of Science:

  • Cardiology
  • Nuclear Medicine
  • Pharmacology

Background:

  • Rapid atrial fibrillation is a common cardiac arrhythmia.
  • Pharmacologic stress myocardial perfusion imaging is used to assess for myocardial ischemia.
  • Takotsubo cardiomyopathy is a form of non-ischemic cardiomyopathy.

Observation:

  • An elderly female patient presented with rapid atrial fibrillation.
  • Dipyridamole stress myocardial perfusion imaging was performed for ischemia assessment.
  • Transient electrocardiogram abnormalities, wall motion, and perfusion defects were observed.

Findings:

  • The observed abnormalities resolved completely within one month.
  • The findings were suggestive of Takotsubo cardiomyopathy.
  • This represents a potential association between dipyridamole stress and Takotsubo cardiomyopathy.

Implications:

  • This case may be the first to report Takotsubo cardiomyopathy following dipyridamole stress.
  • Further research may be warranted to explore this association.
  • Clinicians should be aware of this potential complication during pharmacologic stress testing.

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