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Possible allergic reactions to cyclopentolate hydrochloride: case reports with literature review of uses and adverse

L W Jones1, D T Hodes

  • 1Institute of Optometry, London, UK.

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
|January 1, 1991
PubMed

Insights

Cyclopentolate eye drops are generally safe for pediatric eye exams. However, rare allergic-type reactions can occur, necessitating awareness and preparedness among eye care practitioners.

Area of Science:

  • Ophthalmology
  • Clinical Pharmacology

Background:

  • Cyclopentolate is a widely used cycloplegic and mydriatic agent, often the first choice for pediatric eye exams.
  • The 1% solution is commonly used, with a history of few reported side-effects over 30 years.

Observation:

  • Two cases of possible allergic-type reactions following 1% cyclopentolate hydrochloride instillation are presented.
  • Reactions occurred shortly after the administration of cyclopentolate hydrochloride in 'Minims' form.

Findings:

  • While generally safe, cyclopentolate can rarely cause allergic-type reactions.
  • These reactions highlight the need for vigilance even with established medications.

Implications:

  • Ophthalmologists and optometrists should be aware of potential cyclopentolate hypersensitivity.
  • Practitioners should know how to avoid and manage such adverse events during eye examinations.

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