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Cerebral Hemispheres

The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
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Three-Dimensional Shape Modeling and Analysis of Brain Structures
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Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

Human midsagittal brain shape variation: patterns, allometry and integration.

Emiliano Bruner1, Manuel Martin-Loeches, Roberto Colom

  • 1Centro Nacional de Investigación Sobre la Evolución Humana, Burgos, Spain. emiliano.bruner@cenieh.es

Journal of Anatomy
|March 30, 2010
PubMed
Summary
This summary is machine-generated.

This study analyzed midsagittal brain shape in 102 humans, finding limited integration between cortical and subcortical areas, with some correlation in posterior regions. Brain size varied by sex, but shape did not.

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Area of Science:

  • Neuroscience
  • Anthropology
  • Biomedical Engineering

Background:

  • Midsagittal cerebral morphology offers a geometric reference for brain shape and spatial relationships.
  • Understanding brain shape variation is crucial for fields like functional craniology and neuroscience.

Purpose of the Study:

  • To investigate midsagittal brain shape variation in humans.
  • To quantify correlations between morphological features, size, and sex effects.
  • To assess the integration between cortical and subcortical brain areas.

Main Methods:

  • Analysis of midsagittal brain shape in a sample of 102 humans.
  • Quantification of morphological feature correlations.
  • Investigation of allometric effects and sex differences.

Main Results:

  • A single significant covariation pattern was observed, linked to fronto-parietal cortical bulging.
  • Allometric effects were weak for the cortical profile but stronger for posterior subcortical areas.
  • Sex differences were noted in brain size, not shape; cortical and subcortical areas showed limited integration, suggesting modularity, with some posterior correlation.

Conclusions:

  • Human midsagittal brain shape shows limited integration between cortical and subcortical regions.
  • Fronto-parietal cortical bulging is a key pattern of covariation.
  • Findings support modular brain organization and inform hypotheses on brain shape evolution and mechanics.