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Updated: Jun 14, 2026

Effect of Male Accessory Gland Products on Egg Laying in Gastropod Molluscs
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Published on: June 22, 2014

Gene-environment interaction and male reproductive function.

Jonatan Axelsson1, Jens Peter Bonde, Yvonne L Giwercman

  • 1Reproductive Medicine Centre, Skåne University Hospital, Malmö 20502, Sweden.

Asian Journal of Andrology
|March 30, 2010
PubMed
Summary
This summary is machine-generated.

Genetic factors influence male reproductive health by modifying susceptibility to environmental and lifestyle risks. Understanding gene-environment interactions is key to identifying causes of male reproductive disorders.

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Area of Science:

  • Reproductive biology
  • Environmental health
  • Genetics

Background:

  • Environmental and lifestyle factors are implicated in male reproductive function decline.
  • Individual susceptibility to these factors may be influenced by genetic variants.
  • The interplay between genes and environment in male reproduction is not fully understood.

Purpose of the Study:

  • To critically review evidence on how genes modify environmental effects on male reproductive function.
  • To explore the role of gene-environment interactions in male reproductive disorders.
  • To discuss gene-environment interactions concerning sperm DNA damage and offspring health.

Main Methods:

  • Literature review of animal and human studies.
  • Analysis of evidence on gene-environment interactions in male reproduction.
  • Discussion of implications for reproductive health and disease.

Main Results:

  • Some evidence supports the mechanism of genes modifying environmental effects on male reproduction.
  • Studies on gene-environment interactions in this field are limited.
  • Gene-environment interactions may contribute to male reproductive disorders and sperm DNA damage.

Conclusions:

  • Gene-environment interactions are crucial for understanding male reproductive health and susceptibility to disorders.
  • Further research is needed to elucidate these interactions and their impact on offspring.
  • Identifying genetic predispositions can help mitigate risks associated with environmental exposures.