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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
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Diffusion tensor imaging in a human PET/MR hybrid system.

Andreas Boss1, Armin Kolb, Matthias Hofmann

  • 1Department of Diagnostic and Interventional Radiology, Eberhard-Karls University of Tübingen, Tübingen, Germany. andreas.boss@med.uni-tuebingen.de

Investigative Radiology
|March 31, 2010
PubMed
Summary
This summary is machine-generated.

This study demonstrates that diffusion tensor imaging (DTI) can be performed simultaneously with positron emission tomography (PET) data acquisition using a hybrid PET/MR system. While some artifacts occurred, DTI and PET provided valuable clinical information for brain tumor treatment planning.

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Area of Science:

  • Neuroimaging
  • Medical Physics
  • Radiology

Background:

  • Hybrid positron emission tomography (PET)/magnetic resonance (MR) imaging systems offer potential for simultaneous data acquisition.
  • Diffusion tensor imaging (DTI) is a valuable MRI technique for assessing white matter integrity.

Purpose of the Study:

  • To evaluate the feasibility of simultaneous PET and DTI data acquisition using a hybrid PET/MR scanner.
  • To assess the image quality and accuracy of DTI performed concurrently with PET scans.

Main Methods:

  • Utilized a prototype hybrid PET/MR scanner for brain and head imaging.
  • Acquired DTI data during simultaneous PET data readout in 7 volunteers and 4 brain tumor patients.
  • Compared DTI image quality and accuracy with scans acquired after PET scanner removal.

Main Results:

  • DTI images showed good quality, with no significant differences in fractional anisotropy or principal eigenvector direction between simultaneous and non-simultaneous acquisition.
  • Significantly stronger rim artifacts were observed in fractional anisotropy images during simultaneous PET acquisition due to eddy currents.
  • PET and DTI provided crucial additional clinical information for all 4 patients with brain tumors.

Conclusions:

  • Simultaneous PET and DTI acquisition is feasible with hybrid PET/MR systems.
  • This combined approach offers valuable morphologic and functional insights for brain tumor treatment planning.