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A Web Tool for Generating High Quality Machine-readable Biological Pathways
Published on: February 8, 2017
Collaborative authoring of biomedical terminologies using a semantic Wiki
Shan He1, Senthil K Nachimuthu, Shaun C Shakib
1Department of Biomedical Informatics, University of Utah, Salt Lake City, UT and 3M Health Information Systems, Murray, UT, USA.
Abstract:
To be broadly useful, biomedical terminologies need to capture the knowledge and expertise of multiple experts, research groups and end users. Consequently, the construction of such a terminology requires collaboration among multiple participants. This paper summarizes several terminology projects which employ a collaborative authoring mode in development, along with the various tools used by these projects to support collaboration, such as mailing list, issue tracking system, client-side GUI software and Wiki system. We then discuss the essential functional requirements for a collaborative authoring tool in the context of terminology development, and analyze the inherent features of Semantic Wiki that enable it to be a competent tool used in this type of effort. To demonstrate, we describe a prototype system of collaborative authoring for health care terminologies built upon the Semantic Wiki technology. Finally, we discuss the potential issues that might be associated with this open Semantic Wiki platform.
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Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
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