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Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...

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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

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Published on: June 16, 2014

Stroke in chronic kidney disease.

P Rama Krishna1, S Naresh, G S R Krishna

  • 1Department of Nephrology, Sri Venkateswara Institute of Medical Sciences, Tirupati, India.

Indian Journal of Nephrology
|March 31, 2010
PubMed
Summary
This summary is machine-generated.

Chronic kidney disease (CKD) increases stroke risk. This study details stroke

Keywords:
Chronic kidney diseasediabeteshypertensionstroke

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Area of Science:

  • Nephrology
  • Neurology
  • Clinical Medicine

Background:

  • Chronic kidney disease (CKD) is a known risk factor for cerebrovascular events, particularly stroke.
  • Existing research primarily originates from developed nations, necessitating localized data.
  • Understanding the interplay between CKD and stroke is crucial for patient management.

Purpose of the Study:

  • To investigate the clinical characteristics, management strategies, and outcomes of stroke in patients with CKD.
  • To identify demographic and comorbidity patterns associated with stroke in this population.
  • To determine the etiological subtypes and treatment approaches for stroke in CKD patients.

Main Methods:

  • Prospective observational study.
  • Inclusion of patients admitted with stroke and diagnosed with CKD between December 2004 and December 2006.
  • Data collection on demographics, comorbidities (hypertension, diabetes), stroke type, CKD detection timing, interventions, and outcomes.

Main Results:

  • Stroke incidence was higher in men and those in their fifth decade of life.
  • Hypertension (88.8%) and diabetes (48.1%) were highly prevalent comorbidities.
  • CKD was newly diagnosed during stroke evaluation in 55.5% of cases; cerebral infarction occurred in 48.14% and cerebral hemorrhage in 40.7%.
  • Medical management was employed in most cases (85.2%), with surgical intervention in 14.8%.
  • Over 70% of patients showed symptomatic improvement upon discharge.

Conclusions:

  • Stroke in CKD patients presents with significant comorbidity burden, often with newly diagnosed CKD.
  • Cerebral infarction and hemorrhage are common stroke types in this cohort.
  • While medical management is predominant, a subset requires surgical intervention, with a majority experiencing symptomatic improvement.