Related Experiment Video
Updated: Jun 14, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
Published on: July 19, 2018
[Effects of irrigating fluid absorption in percutaneous nephrolithotripsy]
Ming-Hua Ren1, Shao-Bin Ni, Qi-Yin Chen
1Department of Urology, First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Low pressure and short irrigation times are safe during percutaneous nephrolithotripsy. Prolonged irrigation and bleeding increase risks of congestive heart failure and post-operative infections.
Area of Science:
- Nephrology
- Urology
- Surgical Technology
Context:
- Percutaneous nephrolithotripsy (PCNL) is a common procedure for kidney stone removal.
- Irrigation fluid management during PCNL is critical for patient safety.
- Understanding the impact of irrigation time on hemodynamic status and complications is essential.
Purpose:
- To evaluate the hemodynamic status, fluid-electrolyte balance, and complications related to irrigation time in PCNL.
- To identify risk factors associated with prolonged irrigation during PCNL.
- To establish safe irrigation parameters for PCNL procedures.
Summary:
- This study analyzed 68 PCNL patients, monitoring hemodynamic parameters, fluid-electrolyte levels, and complications.
- Results showed no significant changes in central venous pressure (CVP), heart rate, or electrolytes, but mean arterial pressure (MAP) increased with longer irrigation and bleeding.
- Increased irrigation time correlated with higher fever rates and elevated CVP, while furosemide administration helped reduce CVP.
Impact:
- Findings suggest that maintaining low pressure and short irrigation times in PCNL is safe.
- Prolonged irrigation and significant bleeding are associated with increased risks of congestive heart failure and post-operative infections.
- This research provides evidence-based recommendations for optimizing PCNL procedures to minimize patient morbidity.
Related Concept Videos
Urinary Tract Calculi VI: Surgical Management
Acute Kidney Injury V: Interprofessional Care
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi V: Nursing Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention