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Updated: Jun 14, 2026
Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
[The effect of NaCl solution with different concentration on the resuscitation of hemorrhagic shock]
Wei-xing Wang1, Si-ping Hu, He-fen Wu
1Department of Anesthesiology, Central Hospital of Huzhou, Huzhou 313000, China.
Objective:
To observe the clinical results of different concentration NaCl solution in hemorrhagic shock resuscitation.
Methods:
The 75 cases with hemorrhagic shock were divided into five groups by means of random number table. Treat the cases with 0.9% (control group), 3%, 4.5%, 6% and 7.5% NaCl solution, respectively. Observe the changes of BP, HR, blood gas, renal function, electrolyte concentration of plasma, before and after treatment.
Results:
After transfusion, compared with groups of 0.9% NS, the mean BP of patients in other four groups rise more quickly but only the group of 4.5% can last 30 minutes (P < 0.05), and K(+) of plasma in groups of 6%, 7.5% NS decline more obviously (P < 0.05), the group of 4.5% maintain the best lever.
Conclusion:
The mean BP of patients rise quickly and continue for a long time, in the group of 4.5%. Meanwhile the internal environment of the body maintain relatively stable in the group of 4.5%.
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