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Updated: Jun 14, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Contrast enhanced transesophageal echocardiographic guidance of left atrial appendage closure device implantation
Michael L Main1, George G Latus, Anthony Magalski
1Saint Luke's Mid America Heart Institute, Kansas City, MO, USA. mmain@cc-pc.com
Insights
Percutaneous left atrial appendage closure offers an alternative to anticoagulation for stroke risk in atrial fibrillation. Contrast-enhanced transesophageal echocardiography precisely guided device implantation, enabling warfarin cessation.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Procedures
Background:
- Nonvalvular atrial fibrillation increases stroke risk, often managed with oral anticoagulation.
- Left atrial appendage (LAA) closure devices provide an alternative to anticoagulation.
- Transesophageal echocardiography (TEE) is crucial for LAA assessment and device guidance.
Observation:
- A case study involving a patient with nonvalvular atrial fibrillation requiring LAA closure.
- Challenges in defining LAA anatomy for optimal device placement were noted.
- Contrast-enhanced TEE was employed to overcome these anatomical challenges.
Findings:
- Contrast-enhanced TEE provided critical spatial resolution of LAA borders.
- This enhanced visualization facilitated precise device implantation.
- Successful LAA closure led to the cessation of warfarin therapy.
Implications:
- Contrast-enhanced TEE is a valuable tool for complex LAA closure procedures.
- This technique can improve procedural success rates and patient outcomes.
- It expands treatment options for patients with atrial fibrillation unsuitable for long-term anticoagulation.
Abstract:
The percutaneous implantation of a left atrial appendage closure device offers an alternative to chronic oral anticoagulation in patients with nonvalvular atrial fibrillation and concomitant risk factors for stroke. Transesophageal echocardiography plays a key role in defining left atrial appendage anatomy and in guiding device implantation. The authors describe a case in which contrast-enhanced transesophageal echocardiography was critically important in spatially resolving the borders of the left atrial appendage, which ultimately led to successful device implantation with cessation of warfarin therapy.

