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False-positive IgM serology in coccidioidomycosis
Tim Kuberski1, Judith Herrig, D Pappagianis
1Infection Prevention Program/Quality Management, John C. Lincoln Health Network, 2423 West Dunlap Avenue, Suite 100, Phoenix, AZ 85021, USA. tjkubs@aol.com
Abstract:
The clinical observation has been made that there might be an unacceptable number of false-positive enzyme immunoassay (EIA) test results for IgM among persons suspected of having coccidioidomycosis. Patients with a positive result for IgM by EIA are thought to have a diagnosis of acute coccidioidomycosis. However, this study found that 82% of patients with an IgM-positive and IgG-negative EIA result did not have coccidioidomycosis.
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