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Updated: Mar 29, 2026

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Reactivation of coccidioidomycosis: a prosthetic joint infection in Spain
L Arbeloa-Gutierrez1,2, T Kuberski3, S M Johnson4
1Orthopedics and Traumatology, Complejo Hospitalario de Navarra, C/Irunlarrea n3, 31008, Pamplona, Spain.
Abstract:
A resident of Spain was found to have a prosthetic knee infection due to coccidioidomycosis. He had a history of having pneumonia which resolved while living in an area of California endemic for Coccidioides in 1957-1961. The patient left California in 1961 returned to Spain and never left Spain thereafter. In 2006, a total knee replacement was done. In 2013, a prosthetic knee infection was documented due to coccidioidomycosis. By molecular DNA analysis, Coccidioides immitis was identified from the knee tissue, a species most commonly found in California. This represents reactivation of a Coccidioides infection 56 years after leaving the endemic area.
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