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Updated: Jun 14, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

[A case of non-occulsive mesentery ischemia with pulmonary embolism due to protein C deficiency]

Tae Wan Kim1, Sung Youn Choi, Im Ju Kang

  • 1Department of Internal Medicine, Kangbuk Samsung Hospital, Jongno-gu, Seoul, Korea.

The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi
|April 2, 2010
PubMed

Insights

Protein C deficiency can cause dangerous blood clots in unusual places. This case highlights pulmonary embolism and mesenteric ischemia resulting from type 1 protein C deficiency.

Area of Science:

  • Medical Science
  • Hematology
  • Genetics

Background:

  • Protein C is a key anticoagulant protein.
  • Deficiency in Protein C increases the risk of venous thrombosis and thromboembolism.
  • Hereditary Protein C deficiency is typically autosomal dominant with incomplete penetrance.

Observation:

  • A patient presented with pulmonary embolism and mesenteric ischemia.
  • The condition was linked to type 1 Protein C deficiency.
  • Protein C and S deficiencies are associated with increased thrombosis risk.

Findings:

  • Type 1 Protein C deficiency was diagnosed.
  • This deficiency led to severe thrombotic events.
  • Testing Protein C levels and function is crucial for diagnosis.

Implications:

  • This case underscores the severe consequences of Protein C deficiency.
  • Early detection and management of Protein C deficiency are vital.
  • Understanding genetic factors in thrombosis is critical for patient care.

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