Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ventricular dysfunction following direct-current shock atrioventricular junction ablation.

R J Warren1, J K Vohra, W Chan

  • 1Royal Melbourne Hospital, Vic., Australia.

Australian and New Zealand Journal of Medicine
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First Constraint on Atmospheric Millicharged Particles with the LUX-ZEPLIN Experiment.

Physical review letters·2025
Same author

New Constraints on Cosmic Ray-Boosted Dark Matter from the LUX-ZEPLIN Experiment.

Physical review letters·2025
Same author

Dark Matter Search Results from 4.2  Tonne-Years of Exposure of the LUX-ZEPLIN (LZ) Experiment.

Physical review letters·2025
Same author

A new approach for assessing the radioecological risk associated with the legacy discharge of oil derived natural radioactivity in the UK North Sea.

Marine pollution bulletin·2025
Same author

Constraints on Covariant Dark-Matter-Nucleon Effective Field Theory Interactions from the First Science Run of the LUX-ZEPLIN Experiment.

Physical review letters·2024
Same author

Does it run in the family? - Improving radiological risk assessment in the coastal environment using taxonomic and phylogenetic perspectives in macroalgae species.

Marine pollution bulletin·2024
Same journal

Gastroenterological Society of Australia, Annual Scientific Meeting, May 1980.

Australian and New Zealand journal of medicine·2020
Same journal

'A touch of sugar'--a dangerous euphemism still alive and well.

Australian and New Zealand journal of medicine·2001
Same journal

Silent myocardial ischaemia following methysergide overdose.

Australian and New Zealand journal of medicine·2001
Same journal

Extensive jugular and upper limb thrombosis in a patient with factor V Leiden mutation and non-Hodgkin's lymphoma.

Australian and New Zealand journal of medicine·2001
Same journal

Visual loss as the presenting feature of giant cell arteritis.

Australian and New Zealand journal of medicine·2001
Same journal

Lymphoproliferative disease causing angioedema--an uncommon association.

Australian and New Zealand journal of medicine·2001
See all related articles

Direct-current shock His bundle ablation for supraventricular arrhythmias can impair ventricular function. This study found reduced ejection fraction and wall motion three months post-ablation, suggesting potential myocardial damage or barotrauma.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Catheter-induced His bundle ablation is a common treatment for refractory supraventricular arrhythmias.
  • Direct-current shock energy (200-300 joules) is typically used, creating an atrioventricular node lesion via fulguration.

Purpose of the Study:

  • To assess the impact of direct-current shock His bundle ablation on global and regional ventricular function.
  • To evaluate potential myocardial damage or barotrauma as causes for observed functional changes.

Main Methods:

  • Radionuclide ventriculography was performed on 14 patients before and three months after ablation.
  • Ventricular pacing at 110 bpm was maintained during all studies.
  • Global left ventricular ejection fraction and regional wall-motion scores were analyzed.

Related Experiment Videos

Main Results:

  • Global left ventricular ejection fraction significantly decreased at three months post-ablation (0.43 +/- 0.03 vs. 0.50 +/- 0.03, p=0.02).
  • Six of seven patients with normal baseline wall motion showed significant reduction, primarily at ventricular apices.
  • Deterioration in ventricular function was observed post-ablation.

Conclusions:

  • Direct-current shock His bundle ablation may lead to reduced ventricular function.
  • Myocardial damage from electro-coagulation or barotrauma are potential mechanisms.
  • Further research into less traumatic energy sources for this procedure is warranted.