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Updated: Jun 14, 2026

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
[Esophageal melanoma: report of two cases]
Jean M Butte1, Alvaro Visscher, Hernán DE LA Fuente
1Servicio de Cirugía Digestiva Oncológica, Instituto Oncológico Fundación Arturo López Pérez, Santiago, Chile.
Abstract:
Esophageal melanomas correspond to 0.1 to 0.2% of esophageal tumors. We report two patients with the disease. The first patient is a 51 year-old woman pre-sentingwith dysphagia and weight loss. An upper gastrointestinal endoscopy showed a polypoid ulcerated lesion in the middle third of the esophagus. The pathological study ofthe biopsy disclosed a malignant melanoma. The patient was subjected to an esophagectomy with a satisfactory postoperative evolution. Four months later, liver metastases were detected and the patient died eleven months after the operation. The second patient is a 59 year-old mole that consulted by dysphagia. An endoscopy showed a pigmented esophageal lesion whose pathological diagnosis was a malignant melanoma. The patient was subjected to an esophagectomy and sixteen months after surgery there was no evidence of relapse.
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