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[Differentiation of geographic biovariants of smallpox virus by PCR]

I V Babkin, I N Babkina

    Molekuliarnaia Genetika, Mikrobiologiia I Virusologiia
    |April 6, 2010
    PubMed

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    Smallpox01:24

    Smallpox

    Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.