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Impact of high and low aspiration parameters on postoperative outcomes of phacoemulsification: randomized clinical
Abhay R Vasavada1, Mamidipudi R Praveen, Vaishali A Vasavada
1Iladevi Cataract & IOL Research Centre, Raghudeep Eye Clinic, Ahmedabad, India. icirc@abhayvasavada.com
Purpose:
To compare the effects of fluidic parameters on the central corneal thickness (CCT), corneal endothelium, and anterior segment inflammation after phacoemulsification with longitudinal ultrasound.
Setting:
Iladevi Cataract & IOL Research Center, Ahmedabad, India.
Methods:
In this prospective randomized patient- and examiner-masked study, consecutive patients with age-related cataract were randomly assigned to Group 1 (low fluidic parameters: aspiration flow rate 25 cc/min; bottle height 70 cm and 90 cm; vacuum
Results:
The mean change in CCT from preoperatively to 1 day postoperatively was -6.49% +/- 2.7% in Group 1 and -13.44% +/- 4.3% in Group 2 and from preoperatively to 7 days, -1.74% +/- 1.3% microm and -5.55% +/- 4.3%, respectively (both P<.001). There was no statistically significant difference in the rate of change in ECD between groups from preoperatively to 3 months postoperatively (4.67% +/- 0.15% versus -5.22% +/- 2.84% (P = .45). Anterior chamber flare, cells, and corneal clarity at 1 day were significantly better in Group 1 than in Group 2.
Conclusion:
Low fluidic parameters led to a lower increase in CCT 1 day and 7 days postoperatively, decreased anterior segment inflammation at 1 day, and yielded clear corneas.