Related Experiment Video
Updated: Jun 14, 2026

Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies
Published on: July 19, 2024
A multicenter, prospective, advanced diagnostic bronchoscopy outcomes registry.
Armin Ernst1, Michael Simoff, David Ost
1Division of Interventional Pulmonology and Thoracic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 1 Deaconess Rd, Deaconess 201A, Boston, MA 02215, USA. aernst@bidmc.harvard.edu
This study shows that advanced bronchoscopic procedures achieve a 75% diagnostic yield. Ongoing data analysis is valuable for improving diagnostic accuracy and comparing technologies.
Area of Science:
- Pulmonology
- Interventional Pulmonology
- Diagnostic Bronchoscopy
Background:
- Limited data exists on the comparative performance of new diagnostic bronchoscopic technologies.
- Assessing diagnostic yields, morbidity, and mortality of advanced bronchoscopic procedures is crucial.
Purpose of the Study:
- To establish a multi-institutional prospective-outcomes database for advanced diagnostic bronchoscopic procedures.
- To assess the diagnostic yields, morbidity, and mortality associated with these procedures.
Main Methods:
- Data collected from a paper-based, prospective, multi-institutional outcomes database.
- Included demographics, procedure details, lesion characteristics, and complications.
- Descriptive statistical analyses were performed.
Main Results:
- 310 procedures were performed by 15 clinicians across four institutions over one year.
- Transbronchial needle aspiration (TBNA) was the most common procedure (n=198).
- Overall diagnostic yield was 75% with low complication rates.
Conclusions:
- Prospective data analysis of bronchoscopic procedures is feasible and beneficial.
- Lesion-adjusted yields can aid in comparative assessments and quality improvement.
- Expanding center participation and utilizing web-based submission are future steps.
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