Fitz-Hugh-Curtis Syndrome: single centre experiences

Area of Science:

• Hepatology
• Gastroenterology
• Gynecologic Surgery

Background:

• Fitz-Hugh-Curtis Syndrome (FHCS) is characterized by perihepatic inflammation.
• Diagnosis often relies on clinical presentation and imaging, but can be challenging.
• Laparoscopy is a key diagnostic tool for identifying FHCS and related lesions.

Purpose of the Study:

• To report cases of FHCS diagnosed via CT and laparoscopy.
• To analyze the incidence and characteristics of FHCS-like lesions during gynecological laparoscopies.
• To emphasize the need for considering diverse etiologies and clinical classifications for FHCS.

Main Methods:

• Retrospective review of 3,674 laparoscopic procedures for obstetrical and gynecological conditions.
• Analysis of 10 confirmed FHCS cases diagnosed by clinical findings and CT scans.
• Identification and categorization of 101 FHCS-like lesions observed during laparoscopy.

Main Results:

• Ten cases of FHCS were diagnosed, all exhibiting liver capsular enhancement on CT.
• A 2.7% incidence of FHCS-like lesions was found among the laparoscopies.
• FHCS-like lesions were associated with various gynecological conditions, including endometriosis, tumors, and pelvic inflammatory disease.

Conclusions:

• The study underscores that Fitz-Hugh-Curtis Syndrome can present with diverse clinical phases.
• Causes of FHCS beyond *N. gonorrhoeae* and *C. trachomatis* require further investigation.
• Revised clinical classifications and broader etiological considerations are essential for effective FHCS management.