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Updated: Jun 14, 2026

Study of Experimental Organ Donation Models for Lung Transplantation
Published on: March 15, 2024
Undetermined cause and manner of death after organ/tissue donation
Dwayne A Wolf1, Sharon M Derrick
1Harris County Medical Examiner Office, Houston, TX 77054, USA. dwayne.wolf@meo.hctx.net
Insights
The Harris County Medical Examiner's Office (HCME) faces challenges in determining cause of death when organ procurement organizations recover organs against medical examiner objections. This conflict hinders investigations, leaving the manner of death undetermined in critical cases.
Area of Science:
- Forensic Pathology
- Organ Donation
- Public Health
Background:
- The Harris County Medical Examiner's Office (HCME) supports organ and tissue donation through established protocols.
- Standardized procedures and 24-hour liaison access facilitate donation processes.
Purpose of the Study:
- To examine cases where organ recovery conflicts with the medical examiner's determination of cause and manner of death.
- To illustrate the impact of organ procurement decisions on forensic investigations.
Main Methods:
- Review of five specific organ donation cases.
- Analysis of instances where organ recovery proceeded despite medical examiner objections.
- Evaluation of cases with incomplete or erroneous information leading to organ release.
Main Results:
- In four infant death cases, organ recovery occurred against HCME requests, rendering autopsies incomplete.
- In one case, organ release based on flawed information also compromised the investigation.
- The cause and manner of death remained undetermined in all presented cases due to these conflicts.
Conclusions:
- Conflicts between organ procurement organizations and medical examiners can impede the determination of cause and manner of death.
- The HCME's mission to determine cause of death is compromised when organ recovery overrides objections.
- Clearer protocols and inter-agency communication are crucial to balance organ donation with forensic investigation needs.
Abstract:
The Harris County Medical Examiner's Office (HCME) is proactive and supportive with regard to organ and tissue donation. Steps taken to facilitate donation include development of standardized multiagency protocols for organ/tissue requests and transfer of decedents out of the facility for tissue recovery prior to autopsy. The organ/tissue agencies have 24-hour access to a liaison staff member. No blanket denials are issued for any case type; instead each case is evaluated for feasibility of donation. In rare instances donation of one or more organs is considered detrimental to the mission of determining cause and manner of death. In these cases, the HCME requests that specific organ(s) not be recovered. In this jurisdiction, the organ procurement organization often proceeds with organ recovery despite medical examiner objection. In such cases, the autopsy examination is incomplete and the cause of death cannot be determined. A series of 5 organ donation cases are presented for illustration. Four of these cases are infant deaths in which the HCME requested specific organs not be donated. In the fifth case no denial was issued, but release was granted on incomplete or erroneous information. The cause and manner of death in each case remains undetermined.
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