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Related Concept Videos

Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
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Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

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Related Experiment Video

Updated: Jun 14, 2026

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome
06:51

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome

Published on: July 28, 2023

Decision-making in surgical neonatal necrotizing enterocolitis.

Mitul Parikh1, Ram Samujh, Ravi Prakash Kanojia

  • 1Department of Pediatric Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Journal of Indian Association of Pediatric Surgeons
|April 9, 2010
PubMed
Summary

Predicting surgical neonatal necrotizing enterocolitis (NEC) progression is crucial. Acidosis, high base deficit, and shock indicate a higher likelihood of requiring laparotomy and poorer survival in neonates with NEC.

Keywords:
Laboratory parametersmetabolic acidosisnecrotizing enterocolitisneonateperitoneal drain

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Last Updated: Jun 14, 2026

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome
06:51

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome

Published on: July 28, 2023

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
05:39

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis

Published on: November 30, 2021

Area of Science:

  • Neonatal surgery
  • Pediatric gastroenterology
  • Critical care medicine

Background:

  • Neonatal necrotizing enterocolitis (NEC) is a severe gastrointestinal emergency.
  • Surgical management is often required for advanced NEC.
  • Predictive markers for NEC progression and outcomes are essential.

Purpose of the Study:

  • To identify clinical and laboratory parameters predicting disease progression.
  • To determine factors predicting the need for laparotomy in patients managed with peritoneal drain.
  • To assess predictors of mortality in surgical NEC.

Main Methods:

  • Retrospective study of 27 neonates with surgical NEC.
  • Evaluation of clinical, laboratory (pH, base deficit, platelets), and radiological parameters.
  • Comparison between survivors and non-survivors, drain vs. laparotomy, and disease stages.

Main Results:

  • Mortality rate was 37%.
  • Acidosis, higher base deficit, and shock at admission predicted the need for laparotomy.
  • Progressive fall in platelet counts was observed in patients requiring laparotomy.
  • Absence of shock at presentation correlated with better survival.

Conclusions:

  • Low pH, high base deficit, and shock are significant predictors of laparotomy requirement.
  • These parameters also indicate a higher risk of mortality in surgical NEC patients.
  • Certain clinical and laboratory findings can guide management decisions in neonatal NEC.