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Updated: Jun 14, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
Chiral CE-MS
Carolina Simó1, Virginia García-Cañas, Alejandro Cifuentes
1Department of Food Analysis, Institute of Industrial Fermentations (CSIC), Madrid, Spain.
Abstract:
This review article addresses the developments and applications of capillary electromigration methods coupled on-line with MS for chiral analysis. The multiple enantiomeric applications of this hyphenated technology are covered including chiral analysis of drugs, food compounds, pesticides, natural metabolites, etc. in different matrices such as plasma, urine, medicines, foods, etc. This work intends to provide an updated overview (including works published till September 2009) on the principal chiral applications carried out by CZE-MS, CEC-MS and MEKC-MS, discussing their main advantages and drawbacks in all their different areas of application as well as their foreseeable development in the not too distant future.
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