Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

2° Amines to N-Nitrosamines: Reaction with NaNO2

2° Amines to N-Nitrosamines: Reaction with NaNO₂

Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.

Precipitation Gravimetry

Precipitation Gravimetry

Precipitation gravimetry is based on converting an analyte into a sparingly soluble precipitate, which is separated by filtration and weighed. An ideal precipitate should be pure, insoluble, of known composition, and easily filtered from the reaction mixture.
In determining nickel by gravimetric analysis, a precipitant of ethanolic dimethylglyoxime is added to a hot nickel salt solution. This is quickly followed by the dropwise addition of dilute ammonia solution until precipitation occurs. A...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Validated method for measuring airborne concentrations of tert-butylphenols for occupational exposure assessment.

Journal of occupational health·2026

Same author

A method for simultaneously determining both the inhalable fraction and vapor concentration to assess worker exposure to tri-n-butyl phosphate.

Journal of occupational health·2025

Same author

Air sampling and analysis method to determine worker exposure levels to N-isopropyl-N'-phenyl-p-phenylenediamine.

Journal of occupational health·2025

Same author

A method for determining workers' exposure concentration to airborne nitrilotriacetic acid.

Journal of occupational health·2025

Same author

Degree of twist in the Achilles tendon interacts with its length and thickness in affecting local strain magnitude: a finite element analysis.

Frontiers in bioengineering and biotechnology·2024

Same author

Urinary benzyl alcohol and hippuric acid in workers exposed to benzyl alcohol during paint-stripping work.

Journal of occupational health·2024

Search research articles

Related Experiment Video

Updated: Jun 14, 2026

Automated, High-resolution Mobile Collection System for the Nitrogen Isotopic Analysis of NOx

Automated, High-resolution Mobile Collection System for the Nitrogen Isotopic Analysis of NO_x

Published on: December 20, 2016

Determination method for nitromethane in workplace air.

Akito Takeuchi¹, Yasuki Nishimura, Yuichiro Kaifuku

¹Osaka Occupational Health Service Center, Japan Industrial Safety and Health Association, 2-3-8 Tosabori, Nishi-ku, Osaka, Japan. a-takeuchi@jisha.or.jp

Journal of Occupational Health

|April 10, 2010

Summary

A new method effectively measures nitromethane (NM) in workplace air using activated carbon samplers and gas chromatography. This technique is crucial for assessing worker exposure risks and ensuring safety compliance.

More Related Videos

Detection of 3-Nitrotyrosine in Atmospheric Environments via a High-performance Liquid Chromatography-electrochemical Detector System

Detection of 3-Nitrotyrosine in Atmospheric Environments via a High-performance Liquid Chromatography-electrochemical Detector System

Published on: January 30, 2019

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

Related Experiment Videos

Last Updated: Jun 14, 2026

Automated, High-resolution Mobile Collection System for the Nitrogen Isotopic Analysis of NOx

Automated, High-resolution Mobile Collection System for the Nitrogen Isotopic Analysis of NO_x

Published on: December 20, 2016

Detection of 3-Nitrotyrosine in Atmospheric Environments via a High-performance Liquid Chromatography-electrochemical Detector System

Detection of 3-Nitrotyrosine in Atmospheric Environments via a High-performance Liquid Chromatography-electrochemical Detector System

Published on: January 30, 2019

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

Area of Science:

Occupational Health and Safety
Analytical Chemistry
Environmental Monitoring

Background:

Nitromethane (NM) is used in various industrial applications.
Accurate workplace air monitoring is essential for risk assessment and worker protection.
Existing methods may lack the sensitivity or practicality for comprehensive NM exposure assessment.

Purpose of the Study:

To develop and validate a reliable method for determining nitromethane (NM) concentrations in workplace air.
To establish a method suitable for both personal exposure monitoring and general working environment measurements.
To provide a tool for accurate risk assessment of occupational NM exposure.

Main Methods:

Utilized bead-shaped activated carbon tubes for sampling NM from workplace air.
Employed acetone for desorbing NM from the activated carbon.
Analyzed desorbed NM using a gas chromatograph with a flame ionization detector.
Conducted recovery tests, assessed detection limits, reproducibility, and storage stability.

Main Results:

Achieved high recovery rates for NM (81-97% for personal monitoring, 80-98% for environment measurement).
Established a limit of quantification (LOQ) of 2 microg/sample.
Demonstrated good overall reproducibility with a relative standard deviation of 1.1-4.0%.
Found that sample storage stability decreased significantly over time, especially for lower NM concentrations.

Conclusions:

The developed method provides accurate and reproducible measurements of NM in workplace air.
The method is suitable for 4-hour personal exposure monitoring and 10-minute working environment measurements.
This validated technique is valuable for assessing worker exposure to NM and ensuring compliance with occupational exposure limits.