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Updated: Jun 14, 2026

Intracranial Pharmacotherapy and Pain Assays in Rodents
Published on: April 9, 2019
[Treatment of acute pain during drug-assisted rehabilitation]
Olav Magnus S Fredheim1, Torkjell Nøstdahl, Berit Nordstrand
1Nasjonalt kompetansesenter for sammensatte lidelser og Norges teknisk-naturvitenskapelige universitet og Klinikk for akuttmedisin, Sykehuset Telemark, 3710 Skien, Norway. olav.m.fredheim@ntnu.no
Abstract:
Patients on drug-assisted rehabilitation have the same right to pain relief as others. Techniques that reduce the need for opioids should be used when possible in opioid-dependent individuals who need treatment of acute and post-operative pain. Substitution treatment should always be continued. In some situations a switch to a different opioid or route of administration is required. Higher doses of opioids than those needed in other patients may be required for analgesia. Well-designed clinical studies are lacking in this field.
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