Granular cell tumor on larynx.

Area of Science:

• Oncology
• Otorhinolaryngology
• Pathology

Background:

• Granular cell tumors (GCTs) are uncommon neoplasms with diverse origins.
• Laryngeal GCTs are rare, often presenting with symptoms like hoarseness or dysphagia.
• Differential diagnosis is critical due to potential mimicry of squamous cell carcinoma.

Purpose of the Study:

• To report a case of laryngeal granular cell tumor.
• To review the literature on laryngeal GCTs.
• To emphasize diagnostic and therapeutic considerations.

Main Methods:

• Histopathological examination and immunohistochemical staining for diagnosis.
• Surgical resection using a laryngomicroscope for treatment.
• Literature review of laryngeal GCT cases.

Main Results:

• A 64-year-old male presented with a laryngeal GCT involving the right true vocal cord.
• The tumor was successfully treated by surgical resection.
• Histopathology and immunohistochemistry confirmed the diagnosis, differentiating it from squamous cell carcinoma.

Conclusions:

• Laryngeal granular cell tumors require accurate histopathological and immunohistochemical diagnosis.
• Complete surgical resection with negative margins is the standard treatment.
• Early diagnosis and complete removal are essential for favorable outcomes.