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Updated: Jun 14, 2026
07:23
Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Clinical progress in impending central retinal vein occlusion
Dong-Hoon Lee1, Seok-Joon Lee, Ie-Na Yoon
1Department of Ophthalmology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
Korean Journal of Ophthalmology : KJO
|April 10, 2010
Summary
Impending central retinal vein occlusion typically affects young individuals and often has a good visual prognosis. However, some cases may progress, indicating potential development into a more severe retinal vein occlusion.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
Background:
- Central retinal vein occlusion (CRVO) prognosis is often unclear in its impending stage.
- Limited data exists on the progression and visual outcomes of impending CRVO.
Purpose of the Study:
- To investigate the clinical progress and visual prognoses of patients diagnosed with impending central retinal vein occlusion.
Main Methods:
- Retrospective review of ten patients diagnosed with impending CRVO.
- Analysis of patient demographics, underlying conditions, observational period, and visual acuity.
Main Results:
- The study included ten patients (average age 31.0 years), predominantly male (80%).
- Initial visual acuity averaged LogMar 0.30, improving to LogMar 0.04 at final follow-up, indicating a generally good prognosis.
- One patient experienced worsening retinal hemorrhage and macular edema, requiring radial optic neurotomy.
Conclusions:
- Impending CRVO primarily affects young patients and usually presents with a favorable visual prognosis.
- A subset of patients may experience disease progression, suggesting impending CRVO can be a prodromal phase of acute CRVO.
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