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Related Concept Videos

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex. This...
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
Introduction to Special Senses01:26

Introduction to Special Senses

Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive functions.
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
Taste Buds and Receptors01:20

Taste Buds and Receptors

Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...

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Related Experiment Video

Updated: Jun 14, 2026

Live-cell Measurement of Odorant Receptor Activation Using a Real-time cAMP Assay
09:11

Live-cell Measurement of Odorant Receptor Activation Using a Real-time cAMP Assay

Published on: October 2, 2017

Smelling odors, understanding actions.

Federico Tubaldi1, Luca Turella, Andrea C Pierno

  • 1University of Padua, Padua, Italy.

Social Neuroscience
|April 10, 2010
PubMed
Summary
This summary is machine-generated.

The brain processes actions using multiple senses, including smell. This study found that smelling an object activates brain regions involved in action understanding, suggesting olfaction influences how we perceive actions.

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Last Updated: Jun 14, 2026

Live-cell Measurement of Odorant Receptor Activation Using a Real-time cAMP Assay
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Published on: October 2, 2017

Real-time In Vitro Monitoring of Odorant Receptor Activation by an Odorant in the Vapor Phase
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Published on: April 23, 2019

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Area of Science:

  • Neuroscience
  • Cognitive Science
  • Sensory Processing

Background:

  • Action understanding typically relies on visual and auditory cues.
  • The role of olfaction in action perception remains largely unexplored.
  • Multimodal integration is crucial for comprehensive sensory processing.

Purpose of the Study:

  • To investigate whether olfactory cues influence brain regions involved in action understanding.
  • To determine if the sense of smell contributes to multimodal action representations.
  • To explore the neural basis of action perception beyond visual and auditory modalities.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was employed to measure brain activity.
  • Participants observed actions involving objects that were either smelled or seen.
  • Brain responses to smelling an object during a grasping action were compared to a mimed grasp.

Main Results:

  • Activation was observed in temporal, parietal, and frontal brain areas when participants grasped a smelled object.
  • This neural activity differed significantly from observations of a mimed grasp.
  • Superadditive brain activity occurred when the action target-object was both seen and smelled, indicating synergistic sensory integration.

Conclusions:

  • Olfaction plays a significant role in action understanding.
  • The findings support the concept of multimodal action representations in the brain.
  • This research highlights the integration of smell in perceiving and understanding actions, extending beyond traditional visual and auditory processing.