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Updated: Jun 14, 2026

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

Adult intestinal failure.

J Davidson1, A Plumb, H Burnett

  • 1Salford Royal Hospital, Salford, UK. Jdavidson@doctors.org.uk

Clinical Radiology
|April 13, 2010
PubMed
Summary
This summary is machine-generated.

Intestinal failure (IF) compromises nutrition and fluid balance, often stemming from mesenteric root issues. Early recognition and radiology are key for managing IF and its complications.

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Last Updated: Jun 14, 2026

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Area of Science:

  • Gastroenterology
  • Radiology
  • Nutrition Science

Background:

  • Intestinal failure (IF) is the inability of the alimentary tract to adequately digest and absorb nutrients, impacting fluid balance, growth, and overall health.
  • While severe IF is managed in specialized centers, milder forms are widespread and often under-recognized, with initial insults frequently occurring outside of these specialized units.
  • Mesenteric root diseases are a common cause of intestinal failure.

Purpose of the Study:

  • To review the common etiologies of intestinal failure (IF).
  • To outline the general principles for managing IF.
  • To discuss frequent complications associated with IF and the role of diagnostic imaging in patient management.

Main Methods:

  • This review synthesizes current knowledge on intestinal failure.
  • It examines the diagnostic and interventional role of radiology in managing severe IF.
  • Emphasis is placed on radiology's contribution to both initial restorative and later therapeutic phases.

Main Results:

  • Radiology plays a critical role in facilitating enteral and parenteral feeding access.
  • Imaging is essential for controlling sepsis through the drainage of collections.
  • Radiologists map bowel anatomy and quality, identifying complications to guide clinical treatment planning.

Conclusions:

  • Radiology is integral to the multidisciplinary approach to intestinal failure, aiding in initial management and long-term therapeutic strategies.
  • Early recognition and intervention, supported by radiological expertise, are crucial for improving outcomes in patients with IF.
  • The radiologist's role extends from providing access for nutritional support to identifying and managing complications, thereby facilitating restorative therapy.