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Updated: Jun 14, 2026
07:10
Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
Interactions between COPD and outcomes after percutaneous coronary intervention.
Tomas Konecny1, Krishen Somers, Marek Orban
1Mayo Clinic, Rochester, MN, USA.
Chest
|April 13, 2010
Summary
Patients with chronic obstructive pulmonary disease (COPD) face higher mortality and myocardial infarction (MI) risks after percutaneous coronary intervention (PCI). COPD severity significantly worsens these outcomes, highlighting the need for risk stratification.
Area of Science:
- Cardiology
- Pulmonology
- Public Health
Background:
- Chronic obstructive pulmonary disease (COPD) is prevalent in patients undergoing percutaneous coronary intervention (PCI).
- Limited research exists on COPD's impact on PCI outcomes.
- The influence of COPD severity on post-PCI prognosis remains unexamined.
Purpose of the Study:
- To investigate the association between COPD and outcomes following PCI.
- To determine if COPD severity affects mortality and major adverse cardiac events after PCI.
Main Methods:
- Retrospective analysis of 14,346 patients from the Mayo Clinic PCI registry.
- COPD identification using ICD-9 codes and pulmonary function test (PFT) results.
- Comparison of outcomes between COPD and non-COPD cohorts.
Main Results:
- Patients with COPD (n=2,001) had significantly higher rates of all-cause mortality, cardiac mortality, and myocardial infarction (MI) compared to those without COPD (n=12,345).
- Increased COPD severity correlated with higher mortality post-PCI.
- COPD presence and severity were independent risk factors for mortality and MI after PCI.
Conclusions:
- COPD significantly increases long-term mortality, cardiac mortality, and MI risk in PCI patients.
- Worse COPD severity, indicated by PFTs, is linked to reduced post-PCI survival.
- Screening for COPD in PCI candidates can improve risk stratification and guide targeted therapies.
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