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Immunological Memory

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...

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Updated: Jun 14, 2026

A Semi-automated Approach to Preparing Antibody Cocktails for Immunophenotypic Analysis of Human Peripheral Blood

A Semi-automated Approach to Preparing Antibody Cocktails for Immunophenotypic Analysis of Human Peripheral Blood

Published on: February 8, 2016

A comparative method for processing immunological parameters: developing an "Immunogram".

Riccardo Ortolani¹, Paolo Bellavite, Fiorenza Paiola

¹Sezione di Immunologia Clinica, Dipartimento di Patologia Generale, Azienda Ospedaliero-Universitaria di Verona, Verona, Italy. riccardo.ortolani@univr.it

Blood Transfusion = Trasfusione Del Sangue

|April 13, 2010

Summary

This study introduces the Immunogram, a novel method using multiparametric analysis to create a personalized immune system fingerprint. This tool aids in understanding immune cell dynamics and tracking immune health over time.

Keywords:

immune monitoring immunodiagnostics lymphocyte subsets multiparametric analysis systems biology

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Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

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Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

Facilitating the Analysis of Immunological Data with Visual Analytic Techniques

Published on: January 2, 2011

Area of Science:

Immunology
Computational Biology
Medical Diagnostics

Background:

The immune system is a complex network of interacting cells, sensitive to stimuli and interconnected with other physiological systems.
Studying the immune system requires multiparametric tools that account for its dynamic and complex nature.

Purpose of the Study:

To develop a novel method for analyzing and visualizing immune system parameters.
To create a personalized "immunological fingerprint" for individuals.

Main Methods:

Analysis of lymphocyte subpopulations using monoclonal antibodies and six different fluorochromes.
Creation of a comprehensive database of immunological parameters from approximately 8,000 subjects.
Development of comparative analysis calculating percentile ranks against age-matched peers.

Main Results:

Introduction of the "Immunogram," a graphical representation of an individual's immune parameters as a fingerprint.
Development of dedicated software (Immunogramma) for automated analysis and visualization.
Ability to generate dynamic immune profiles and compare patterns across subjects.

Conclusions:

The Immunogram method facilitates the study and longitudinal monitoring of immune parameters.
The automated software enhances data sharing and database expansion, increasing informational capacity for research and clinical applications.