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[Hemorrhagic shock and encephalopathy syndrome in infancy and childhood]

M Kirschstein1, F Aksu, F Tegtmeyer

  • 1Klinik für Pädiatrie, Medizinischen Universität zu Lübeck.

Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
|February 1, 1991
PubMed

Insights

Hemorrhagic shock and encephalopathy syndrome (HSES) presents with severe symptoms like coma and shock in infants. This study details HSES cases, discussing its nature as a distinct disorder or a known condition with a new name.

Area of Science:

  • Pediatrics
  • Neurology
  • Infectious Diseases

Background:

  • Hemorrhagic shock and encephalopathy syndrome (HSES) is a rare but severe condition affecting infants.
  • Early recognition and diagnosis are crucial for managing this potentially life-threatening illness.

Observation:

  • Two infants presented with prodromal diarrhea and fever, followed by abrupt coma, seizures, shock, and hyperpyrexia.
  • Clinical manifestations included bleeding, pancytopenia, and impaired liver and renal function.

Findings:

  • Both infants survived but experienced significant neurologic sequelae.
  • The observed clinical and laboratory findings were consistent with HSES, first described in 1983.

Implications:

  • This case report contributes to understanding the clinical spectrum and diagnostic criteria for HSES.
  • Further research is needed to elucidate the etiology and pathogenesis of HSES and determine if it represents a novel entity or a re-emergence of a known disorder.

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