Related Experiment Video
Updated: Aug 12, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
[Exacerbation of psoriasis caused by malaria prophylaxis with chloroquine and proguanil]
1Academisch Ziekenhuis, afd. Dermatologie en Venereologie, Utrecht.
Abstract:
Two patients with psoriasis vulgaris who travelled to endemic malaria areas developed erythroderma and generalized psoriasis guttata 3-4 weeks after starting prophylactic antimalarial medication with chloroquine/proguanil. The lesions resolved after 3 months of intensive treatment and discontinuation of the antimalarial drugs. The literature on these less known adverse effects of antimalarials in psoriatic patients is reviewed. Because of the severity of a malaria infection we advise psoriasis patients to have adequate malaria prophylaxis.
Related Concept Videos
Symbiosis
Diversity of Protists II
Rocky Mountain Spotted Fever
Cryptococcal Meningitis
Malaria
Antiprotozoal Agents

