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Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Updated: Jun 13, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

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Published on: February 16, 2016

Left ventricular noncompaction.

R Malla1, R Sharma, B Rauniyar

  • 1Department of Cardiology, Shahid Gangalal National Heart Center, Bansbari, Kathmandu, Nepal.

JNMA; Journal of the Nepal Medical Association
|April 15, 2010
PubMed
Summary
This summary is machine-generated.

Left Ventricular Noncompaction (LVNC) is a rare genetic heart condition. Early diagnosis via echocardiography is crucial, as prognosis is poor with limited treatment options.

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Area of Science:

  • Cardiology
  • Genetics
  • Medical Diagnostics

Background:

  • Left Ventricular Noncompaction (LVNC) is an emerging genetic cardiac disease.
  • Clinical signs include heart failure, arrhythmias, embolic events, and in children, facial dysmorphisms and Wolff-Parkinson-White syndrome.
  • Diagnosis is frequently missed due to lack of awareness.

Purpose of the Study:

  • To highlight the importance of recognizing and diagnosing Left Ventricular Noncompaction (LVNC).
  • To emphasize the role of echocardiography in LVNC diagnosis.
  • To underscore the need for screening relatives of affected individuals.

Main Methods:

  • Echocardiography is the gold standard for diagnosing LVNC.
  • Clinical presentation and familial association are key diagnostic considerations.

Main Results:

  • LVNC presents with heart failure, arrhythmias, and embolic events.
  • Prognosis is poor for patients with reduced systolic function.
  • Echocardiography is essential for accurate diagnosis.

Conclusions:

  • Left Ventricular Noncompaction (LVNC) requires greater clinical awareness.
  • Screening first-degree relatives of LVNC patients is recommended due to its genetic nature.
  • Early echocardiographic diagnosis can potentially improve patient outcomes.