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Measuring Blood Pressure in Mice using Volume Pressure Recording, a Tail-cuff Method
Published on: May 15, 2009
[A calibrated method for blood pressure measurement based on volume pulse wave]
Ding Youde1, Deng Qinkai, Liang Feixue
1institute of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515.
Abstract:
Physiology parameters measurement based on volume pulse wave is suitable for the monitoring blood pressure continuously. This paper described that the systolic blood pressure (SBP) and diastolic blood pressure (DBP) can be calibrated by measuring the pulse propagation time, just on one point of finger tip. The volume pulse wave was acquired by lighting the red and infrared LED alternately, and after signal processing, an accelerated pulse wave was obtained. Then by measuring the pulse wave propagation time between the progressive wave and reflected wave, we can find the relationship of the time and the blood pressure, and establish the related systolic blood pressure measurement equation. At the same time, based on the relationship between alternating current and direct current components in the volume pulse waveforms and through regression analysising, the relevant diastolic blood pressure measurement equation can be established. 33 clinical experimentation cases have been worked by dividing them into two groups: training group (18 cases) and control group (15 cases), by comparing with the measuring results of the OMRON electronic sphygmomanometer. The results indicated that the two methods had good coherence. The measurement described is simple and reliable, and may be served as a new method for noninvasively and continuously measurement of blood pressure.
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Monitoring Both Arms:
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