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Updated: Jun 13, 2026

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Published on: August 7, 2017
Predisposing factors for acute otitis media in infancy
Fani Ladomenou1, Anthony Kafatos, Yiannis Tselentis
1Department of Paediatrics, University of Crete, Heraklion 71003, Greece.
Infant acute otitis media (AOM) risk factors include siblings, daycare, maternal illness, and poor breastfeeding. These findings highlight modifiable factors for AOM prevention in infants.
Area of Science:
- Pediatrics
- Epidemiology
- Public Health
Background:
- Acute otitis media (AOM) is a common childhood illness with incompletely understood predisposing factors.
- Identifying risk factors is crucial for developing effective prevention strategies.
Purpose of the Study:
- To prospectively investigate the incidence rates and risk factors associated with AOM in a systematic sample of infants.
- To analyze the relationship between various infant, family, and environmental factors and AOM occurrence.
Main Methods:
- A cohort of 1049 mother-infant pairs was followed for 12 months post-birth.
- Data on AOM episodes were collected via parental reports of physician diagnoses.
- Multivariate analysis was used to assess 21 potential risk factors.
Main Results:
- 28.6% of infants experienced at least one AOM episode; 6.16% had multiple episodes.
- Key risk factors identified included: presence of siblings, out-of-home daycare, maternal ill health during pregnancy, suboptimal breastfeeding, and lower parental education.
- Hospitalization for AOM was associated with younger maternal age.
Conclusions:
- Infant AOM presents significant morbidity, influenced by several identifiable infant and family-related factors.
- The study identifies several factors that may be amenable to intervention for AOM prevention.
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