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Related Experiment Video

Updated: Jun 13, 2026

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
14:24

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model

Published on: January 21, 2018

Current perspectives on imaging cardiac stem cell therapy.

Joseph C Wu1, M Roselle Abraham, Dara L Kraitchman

  • 1Department of Medicine (Cardiology) and Radiology, Stanford University School of Medicine, Stanford, California, USA. joewu@stanford.edu

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|April 17, 2010
PubMed
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Molecular imaging allows noninvasive tracking of stem cells in cardiovascular regenerative therapy. This review covers stem cell types, imaging methods, and challenges for clinical translation of cardiac stem cell imaging.

Area of Science:

  • Regenerative Medicine
  • Molecular Imaging
  • Cardiovascular Science

Background:

  • Cellular and molecular processes in living subjects can be visualized noninvasively using molecular imaging.
  • Tracking cell fate after transplantation is crucial for cardiovascular regenerative therapy's success.
  • Understanding cell location, survival, and adverse effects is essential for effective cell-based therapies.

Purpose of the Study:

  • To review stem cell types used in cardiovascular repair.
  • To discuss the development of in vivo imaging modalities for tracking cardiac stem cell fate.
  • To highlight challenges in the clinical translation of cardiac stem cell imaging.

Main Methods:

  • Literature review of molecular imaging techniques applied to cardiovascular regenerative therapy.

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Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction
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Related Experiment Videos

Last Updated: Jun 13, 2026

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
14:24

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model

Published on: January 21, 2018

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
10:16

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction
06:47

Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction

Published on: July 25, 2025

  • Analysis of stem cell types employed for cardiac repair.
  • Examination of in vivo imaging modalities for cell fate assessment.

    • Main Results:

    • Various stem cells are utilized for cardiovascular repair.
    • Multiple imaging modalities have been developed to track stem cell fate in vivo.
    • Significant challenges exist in translating cardiac stem cell imaging to clinical practice.

    Conclusions:

    • Molecular imaging is vital for advancing cardiovascular regenerative therapy.
    • Effective tracking of transplanted cells is necessary for therapeutic success.
    • Overcoming clinical translation challenges is key for future cardiac stem cell therapies.