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Lipid profile among ischemic and haemorrhagic stroke patients

S K Dey1, S Ahmed, K M Rahman

  • 1Dr Subash Kanti Dey, Registrar, Department of Neurology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh.

Mymensingh Medical Journal : MMJ
|April 17, 2010
PubMed

Insights

Serum lipid profiles, particularly low-density lipoprotein (LDL), show no significant difference between ischemic and hemorrhagic stroke patients, despite being elevated in both groups. This finding is crucial for understanding stroke risk factors.

Area of Science:

  • Neurology
  • Cardiovascular Medicine
  • Clinical Biochemistry

Background:

  • Stroke, a leading cause of disability and death, encompasses both ischemic and hemorrhagic types.
  • Serum lipid profiles are established risk factors for cardiovascular diseases, including stroke.
  • Understanding lipid associations in different stroke subtypes is critical for targeted prevention and treatment strategies.

Purpose of the Study:

  • To investigate the association of serum lipid profile components in patients with ischemic stroke versus hemorrhagic stroke.
  • To compare lipid levels, including total cholesterol, HDL, LDL, and triglycerides, between the two stroke subtypes.

Main Methods:

  • A prospective cross-sectional study was conducted at Mymensingh Medical College Hospital (MMCH).
  • Patients diagnosed with ischemic or hemorrhagic stroke were selected based on specific inclusion and exclusion criteria.
  • Serum lipid profiles were analyzed and compared between the two stroke groups.

Main Results:

  • Both ischemic and hemorrhagic strokes were more prevalent in individuals over 50 years old, with males affected more frequently than females.
  • Risk factors such as smoking, hypertension, and diabetes mellitus were equally common in both stroke types.
  • Low-density lipoprotein (LDL) levels were elevated in both stroke groups, with no statistically significant difference observed between ischemic and hemorrhagic stroke patients (p > 0.05). Total cholesterol, HDL, and triglyceride levels were within normal ranges and showed no significant inter-group differences.

Conclusions:

  • Elevated LDL cholesterol is a common finding in both ischemic and hemorrhagic stroke patients.
  • There are no significant differences in major serum lipid profile components between ischemic and hemorrhagic stroke patients in this cohort.
  • Further research may be needed to explore other potential lipid-related factors or non-lipid biomarkers differentiating stroke subtypes.

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